LEARN ABOUT COENZYME Q10 (COQ10)

December 31, 2021

Learn About Coenzyme Q10 (CoQ10)

Friday, December 31, 2021

image of elderly man and woman embracing

Coenzyme Q10 (CoQ10), is an important nutrient that supports energy metabolism throughout the body.* CoQ10 exists in the membranes of mitochondria making energy metabolism efficient. Its reduced form (ubiquinol) is the active form. By assisting mitochondria, ubiquinol has antioxidant activities and also supports the larger cellular antioxidant network. These two functions, bioenergetic and antioxidant, characterized initial CoQ10 research, while in the new millennium, novel research of CoQ10 highlight its expanding role in aging, and heart and blood vessel health, and its possible future role in immunity, exercise performance, and more.

One of the biggest challenges since the first discovery of CoQ10 about 65 years ago has been how to improve the amount of CoQ10 in the blood by dietary supplementation of CoQ10. Additionally, the standard CoQ10 supplements contain a more oxidized form of CoQ10, called ubiquinone. Scientists now understand that the reduced form of CoQ10 (ubiquinol) is the active antioxidant form of CoQ10. While standard Co-Q10 (ubiquinone) supplements can be reduced to the antioxidant state in the body, this reduction can be less efficient in some individuals due to health status, age or genetics. Ubiquinol also has significantly superior bioavailability to ubiquinone as demonstrated in clinical trials.

The pro-liposomal delivery system in Jarrow Formulas® proprietary QH-absorb® was the breakthrough that allowed for absorption of CoQ10 into the blood. QH-absorb® is a clinically validated and safe carrier to absorb CoQ10 that was first published in 2009. Instead of detergents, QH-absorb® contains all-natural medium chain lipids and monoglycerides that are native to the intestinal cell membranes. Recent research shows that detergents can compromise the gut barrier and allow the incursion of bacteria into the blood stream. Instead, the pro-liposomal delivery system in QH-absorb® improves absorption of the antioxidant reduced form of CoQ10 without any of the potential adverse effects of detergents. QH-absorb® is gentle on the intestine while at the same time improving blood levels of CoQ10.

Eminent CoQ10 scientists from the Polytechnic University of Marche, in Ancona, Italy published the bioavailability of Jarrow Formulas® proprietary QH-absorb® formula: Over a 2-week period, measuring the plasma level of CoQ10 after taking 100 mg three times per day the results proved the superior absorption of QH-absorb® compared to standard CoQ10. Total CoQ10 and antioxidant CoQ10 (ubiquinol) levels increased by over 700% over baseline.

Jarrow Formulas® QH-absorb® is a proprietary stabilized formula that offers improved bioavailability over standard Co-Q10 supplements (ubiquinone), QH-absorb® delivers Co-Q10 in its native antioxidant-capable form at higher levels without detergents.

QH-absorb®, like Q-absorb®, uses an all-natural pro-liposome delivery system to improve absorption. Jarrow Formulas®’ Q-absorb® and QH-absorb® delivery systems have been validated in multiple trials to significantly improve Co-Q10 absorption. Jarrow Formulas® ubiquinol is derived from Co-Q10 that is manufactured via a yeast-fermentation process and consists only of the natural trans configuration, the same as is biosynthesized by humans.

 

+These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

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